Computing and Telecommunications
- .mac, a file extension for macros in Agilent ChemStation
- .Mac, a former name of MobileMe
- MAC address, Media Access Control address or Ethernet Hardware Address (EHA)
- Mac OS, an operating system of Apple's Macintosh
- MAC times, file system metadata which record when an object was last "modified" (contents), "accessed" (read), and "changed" (permissions)
- Macintosh, a brand of personal computers and computer operating systems made by Apple Inc.
- Mandatory access control, a type of access control in computer security
- Media Access Control, sublayer of Data Link layer
- Message authentication code, used to authenticate a message in cryptography
- Migration Authorisation Code, a unique code used when switching between DSL Internet service providers in the UK
- Mission Assurance Category, a designation used in the United States Department of Defense, reflecting the importance of an information system for the successful completion of a DoD mission, especially in regard to availability and integrity
- Multiplexed Analogue Components
- Multiply–accumulate or Multiplier–accumulator
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