Lusk may refer to:
- Lusk, Tennessee, a community in the U.S. state of Tennessee
- Lusk, Wyoming, a town in the U.S. state of Wyoming
- Lusk, Dublin, a village in Ireland
- Lusk, a band that released the album Free Mars in 1997
- Jeremy Lusk, a American freestyle motocross racer
- Clayton R. Lusk (1872-1959), American politician from New York State
- Lusk Committee of the New York State legislature, 1919