Lupescu is a Romanian surname, deriving from the Romanian word lup ("wolf"), from Latin lupus ("wolf"). Its Spanish equivalent is López, its Italian equivalent is Lupo. Lupescu may refer to:
- Magda Lupescu
- Ioan Lupescu
- Nicolae Lupescu
- Valya Dudycz Lupescu
- Miss Lupescu, a character from Neil Gaiman's The Graveyard Book
| This page or section lists people with the surname Lupescu. If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link. |