Filmography
| Year | Film | Role | Other notes |
|---|---|---|---|
| 1963 | A Gathering of Eagles | Mrs. Kemler | uncredited |
| 1974 | Thieves Like Us | Mattie | |
| 1975 | One Flew Over the Cuckoo's Nest | Nurse Mildred Ratched | Academy Award for Best Actress BAFTA Award for Best Actress in a Leading Role Golden Globe Award for Best Actress – Motion Picture Drama Nominated - New York Film Critics Circle Award for Best Supporting Actress |
| Russian Roulette | Midge | ||
| 1977 | Exorcist II: The Heretic | Dr. Gene Tuskin | |
| 1978 | The Cheap Detective | Marlene DuChard | |
| 1979 | Natural Enemies | Miriam Steward | |
| The Magician of Lublin | Emilia | ||
| The Lady in Red | Anna Sage | ||
| 1980 | Mama Dracula | Mama Dracula | |
| The Lucky Star | Loes Bakker | ||
| 1981 | Strange Behavior | Barbara Moorehead | |
| 1983 | Brainstorm | Dr. Lillian Reynolds | Saturn Award for Best Actress |
| Strange Invaders | Mrs. Benjamin | ||
| Overnight Sensation | Eve Peregrine – 'E. K. Hamilton' | ||
| 1984 | Firestarter | Norma Manders | |
| Talk to Me | Richard's mother | ||
| 1986 | Nobody's Fool | Pearl | |
| The Boy Who Could Fly | Psychiatrist | ||
| Invaders from Mars | Mrs. McKeltch | ||
| 1987 | Flowers in the Attic | Grandmother – Olivia Foxworth | Nominated—Saturn Award for Best Supporting Actress |
| Grizzly II: The Predator | Park Supervisor | ||
| 1988 | Two Moon Junction | Belle Delongpre | |
| 1989 | Best of the Best | Mrs. Grady | |
| The Karen Carpenter Story | Agnes Carpenter | ||
| 1990 | Blue Steel | Shirley Turner | |
| Shadowzone | Dr. Erhardt | ||
| 1991 | In A Child's Name | Jean Taylor | |
| 1993–1999 | Star Trek: Deep Space Nine | Winn Adami | |
| 1994 | Giorgino | Innkeeper | |
| Tryst | Maggie | ||
| Tollbooth | Lillian | ||
| Someone Else's Child | Faye | ||
| 1995 | Return to Two Moon Junction | Belle Delongpre | |
| Virtuosity | Elizabeth Deane | ||
| 1996 | The Stepford Husbands | Miriam Benton | |
| Edie & Pen | Judge | ||
| Mulholland Falls | Esther | uncredited | |
| Frankenstein and Me | Mrs. Perdue | ||
| High School High | Principal Evelyn Doyle | ||
| 2 Days in the Valley | Evelyn | ||
| 1997 | Breast Men | Mrs. Saunders | Nominated—Satellite Award for Best Supporting Actress – Series, Miniseries or Television Film |
| The Girl Gets Moe | Gloria | ||
| Gone Fishin' | Restaurant Owner | uncredited | |
| 1998 | Love Kills | Alena Heiss | |
| 1999 | A Map of the World | Nellie Goodwin | |
| Cruel Intentions | Helen Rosemond | ||
| The Contract | Grandma Collins | ||
| 2000 | More Dogs Than Bones | Iva Doll | |
| Very Mean Men | Katherine Mulroney | ||
| Big Eden | Grace Cornwell | ||
| Silver Man | Val | ||
| 2001 | After Image | Aunt Cora | |
| Touched by a Killer | Judge Erica Robertson | ||
| Dial 9 for Love | Abbie | ||
| 2002 | Manna from Heaven | Mother Superior | |
| 2003 | Finding Home | Esther | |
| 2004 | Clipping Adam | Grammy | |
| 2005 | Aurora Borealis | Ruth Shorter | |
| Dancing in Twilight | Evelyn | ||
| ER | Roberta 'Birdie' Chadwick | ||
| 2006 | Fat Rose and Squeaky | Bonnie | |
| Me and Luke | Grandmother Glennie | ||
| 2007 | The Last Sin Eater | Miz Elda | |
| 2009 | Heroes | Doctor Coolidge | |
| 2010 | Private Practice | Pete Wilder's mother | |
| 2012 | Shameless | Peggy Gallagher |
Read more about this topic: Louise Fletcher