Lorena may refer to:
- Lorena, a given name, see Lorena (name)
- Lorena, São Paulo, a municipality in Brazil
- Lorena, California, alternate name of Masonic, California
- Lorena, Texas, a city in McLennan County, Texas
- Lorena (album), a 2007 album by Spanish singer Lorena
- Lorena (song), an 1856 song by Joseph Phillbrick Webster
- Hurricane Lorena (disambiguation), a name for several tropical cyclones on the eastern Pacific Ocean
- Lorena (telenovela), Colombian soap opera
- a type of stove, see Cook stove#Lorena adobe stove