Contraindications and Special Caution
Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, alcohol or drug-dependent individuals and individuals with comorbid psychiatric disorders. Loprazolam, similar to other benzodiazepines and nonbenzodiazepine hypnotic drugs causes impairments in body balance and standing steadiness in individuals who wake up at night or the next morning. Falls and hip fractures are frequently reported. The combination with alcohol increases these impairments. Partial, but incomplete tolerance develops to these impairments.
Read more about this topic: Loprazolam
Famous quotes containing the words special and/or caution:
“It is a maxim among these lawyers, that whatever hath been done before, may legally be done again: and therefore they take special care to record all the decisions formerly made against common justice and the general reason of mankind.”
—Jonathan Swift (1667–1745)
“I cannot say to a person who suffers injustice, “Wait.” Perhaps you can. I can’t. And having decided that I cannot urge caution I must stand with him.”
—Sandra “Casey” Cason (b. c. 1939)