Long NcRNA Functions
Large scale sequencing of cDNA libraries and more recently transcriptomic sequencing by next generation sequencing indicate that long noncoding RNAs number in the order of tens of thousands in mammals. However, despite accumulating evidence suggesting that the majority of these are likely to be functional, only a relatively small proportion has been demonstrated to be biologically relevant. As of December 2012, ~127 LncRNAs have been functionally annotated in LncRNAdb (a database of literature described LncRNAs).
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