Surname
- Andrea Lombardo (born 1987), Canadian football (soccer) player
- Antonio Lombardo (sculptor) (1458–1516), sculptor, son of Pietro Lombardo
- Antonio Lombardo (1892–1928), Italian-American advisor to Al Capone
- Attilio Lombardo (born 1966), Italian football (soccer) player
- Carmen Lombardo (1903–1971), Canadian musician, brother of Guy Lombardo
- Dave Lombardo (born 1965), Cuban-American drummer
- Giovanni Lombardo Radice (born 1954), Italian actor
- Guy Lombardo (1902–1977), Canadian-American bandleader and musician
- John Lombardo (born 1952), American musician (alternative rock band 10,000 Maniacs, folk duo John & Mary)
- Joseph Lombardo (born 1929), American Mafia figure
- Lucio Lombardo-Radice (1916–1982), Italian mathematician
- Massimo Lombardo (born 1973), Swiss footballer
- Matteo Lombardo (born 1985) Italian footballer
- Michelle Lombardo (born 1983), American model and actress
- Pietro Lombardo (1435–1515), Italian sculptor
- Raffaele Lombardo (born 1950), Italian politician
- Rex Lombardo (born 1946), American rope-swing engineer
- Rosalia Lombardo (1918–1920), Italian girl and one of the last people placed in the catacombs of Palermo
- Stanley Lombardo (born 1943), American academic and translator
- Tony Lombardo (contemporary), American punk musician
- Tullio Lombardo (1460–1532), Italian sculptor, son of Pietro Lombardo
- Vicente Lombardo Toledano (1894–1968), Mexican labor leader
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