Lithia may refer to:
- Lithia or lithium oxide, a chemical compound
- Lithia, Florida a unincorporated suburb of Tampa, Florida in the United States
- "Lithia" (The Outer Limits), an Outer Limits television episode
- Lithia water, a type of mineral water
- Lithia (water brand), a brand of lithia water sourced from Lithia Springs, Georgia
- Lithia Brewing, a beer company based in central Wisconsin, later owned and operated by the Walter Brewing Company
- Litha, a solstice festival, is also known as Lithia