16th Century
- 1596
- Willem Barentsz makes the first indisputable discovery of the Svalbard archipelago
- 1591
- Moroccans conquer Timbuktu
- 1580
- Personal union of Spain and Portugal
- 1575
- The capital of Chile is moved from Concepción to Santiago
- 1532
- Francisco Pizzaro conquers the Inca
- 1526
- Babur of the Mughal Empire defeats the sultan of Delhi
- 1522
- Ferdinand Magellan circumnavigates the Earth
- 1519-1521
- Hernando Cortés conquers the Aztecs
- 1513
- Juan Ponce de León claims Florida for Spain
- 1513
- Vasco Núñez de Balboa crosses the Isthmus of Panama
- 1501
- May 20 — João da Nova Castell discovers Ascension Island
Read more about this topic: List Of World Map Changes