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- Magic Knight Rayearth (Sega Saturn, Game Gear, Game Boy, Super Famicom)
- Magical Taluluto (Game Boy, Family Computer, Mega Drive, Game Gear, Super Famicom)
- Mahjong Hishō-den: Naki no Ryū (Sharp X68000, PC-9801, Super Famicom)
- Mahōjin Guru Guru (Super Famicom, Game Boy, Game Boy Color)
- Mahou Sensei Negima (Game Boy Advance, PlayStation 2, Nintendo DS, PlayStation Portable)
- Marmalade Boy (Super Famicom, Game Boy)
- Martian Successor Nadesico: The Blank of Three Years (Sega Saturn)
- Martian Successor Nadesico: The Mission (Dreamcast)
- Mazinger Z (Arcade, Super Famicom)
- Mermaid Melody Pichi Pichi Pitch (Game Boy Advance)
- Mahou no Princess Minky Momo (Famicom)
- Maya the Bee (Game Boy Advance)
- Medabots
- Meine Liebe
- Miracle Girls (Super Famicom)
- Mobile Battleship Nadesico (Sega Saturn)
- Mobile Battleship Nadesico: Ruriruri Mahjong (Game Boy Color)
- Monochrome Factor Cross Road (Japanese PS2s or PS3 only)
- Mōryō Senki MADARA 2
- MS Saga: A New Dawn (PlayStation 2) (a crossover game that featured many mobile suits and was meant to bring in new fans)
- Mugen Senshi Valis (An OVA called "Genmu Senki Leda" was made using the Valis games as a template, but the property itself is unrelated.)
Read more about this topic: List Of Video Games Based On Anime Or Manga