Ms. Keane (voiced by Jennifer Hale in the series and by Kath Soucie in the What a Cartoon! episodes): The kindergarten teacher of Pokey Oaks Kindergarten. She wears an orange shirt, red vest, brown pants, and has short black hair and light blue eyes. She is patient, understanding and very protective of her students, making her a well-liked, motherly figure. She, once upon a time, fell in love with the Professor and went on a date with him in episode "Keen on Keane", but their passion was unfortunately short lived when the Professor found out that Ms. Keane had a cat, since he had a traumatic experience with one in a previous episode as it made him jump off a building.
It should be noted that although Ms. Keane is a kindergarten teacher, she is also incredibly smart. This was shown in the episode "Speed Demon" when she, prior to the girls' time travel, actually tried to figure out how the speed of a person throwing an apple could make said apple travel faster than the speed of light and thus being able to travel though time and space. Soon realizing that she is confusing the children, she returns to her normal state, and excuses herself. Ms. Keane also forbids any fighting in school even if there's a crisis taking place within it thus she convinces the girls that there are other ways to solve problems other than fighting as demonstrated in the episode "Schoolhouse Rocked".
Read more about this topic: List Of The Powerpuff Girls Characters, Citizens of Townsville