Bulgaria
- Regent - Tsarina Maria – 1018 (disputed)
- Regent - Irene Komnene of Epirus – 1246 (disputed)
People's Republic of Bulgaria:
- Government Minister - Tsola Dragoycheva - 1947
Republic of Bulgaria:
- Prime Minister (acting) - Reneta Indzhova - 1994
- Foreign minister (acting) - Irina Bokova - 1996
- President of the National Assembly - Tsetska Tsacheva - 2009
Read more about this topic: List Of The First Female Holders Of Political Offices In Europe