List of Protein Structure Prediction Software - Homology Modeling

Homology Modeling

Name Method Description Link
RaptorX remote homology detection, accurate alignment, 3D modeling Automated webserver server
3D-JIGSAW Fragment assembly Automated webserver server
Biskit wraps external programs into automated workflow BLAST search, T-Coffee alignment, and MODELLER construction project site
CABS Reduced modeling tool Downloadable program download
CPHModel Fragment assembly Automated webserver server
EasyModeller GUI to MODELLER Standalone windows executable download
ESyPred3D Template detection, alignment, 3D modeling Automated webserver server
FoldX Energy calculations and protein design Downloadable program download
GeneSilico Consensus template search/fragment assembly Webserver server
Geno3D Satisfaction of spatial restraints Automated webserver server
HHpred Template detection, alignment, 3D modeling Interactive webserver with help facility server download article
LIBRA I LIght Balance for Remote Analogous proteins, ver. I Webserver server
LOMETS Local Meta threading server Meta-server combining 9 different programs Server

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MODELLER Satisfaction of spatial restraints Standalone program mainly in Fortran and Python download Server
Phyre and Phyre2 Remote template detection, alignment, 3D modeling, multi-templates, ab initio Webserver with job manager, automatically updated fold library, genome searching and other facilities server
Prime Physics-based energy function Graphical interface, sequence alignment, secondary structure prediction, homology modeling, protein refinement, loop-prediction, and side-chain prediction Download
Protinfo CM Comparative modelling of protein structure using minimum perturbation and loop building Web server server
ROBETTA Rosetta homology modeling and ab initio fragment assembly with Ginzu domain prediction Webserver server
BHAGEERATH-H Combination of ab initio folding and homology methods Protein tertiary structure predictions server
Selvita Protein Modeling Platform Package of tools for protein modeling Free demo, interactive webserver and standalone program including: BLAST search, CABS modeling, 3D threading, Psi-Pred secondary structure prediction Home page
SWISS-MODEL Local similarity/fragment assembly Automated webserver (based on ProModII) server
TIP-STRUCTFAST Automated Comparative Modeling Webserver and knowledgebase server
WHAT IF Position specific rotamers Standalone program and webinterface Home page Webinterface
YASARA Detection of templates, alignment, modeling incl. ligands and oligomers, hybridization of model fragments Graphical interface or text mode (clusters) Home page CASP8 results

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