S
- Samantha Who
- Scrubs
- Seinfeld
- Sex and the City
- Sexy Cam
- Shane
- Sister Sister
- skitHOUSE
- Sledge Hammer!
- Soap
- South Park
- Spin City
- Spitting Image
- SpongeBob SquarePants
- Stacked
- Suburban Shootout
Read more about this topic: List Of Programmes Broadcast By Comedy Central (UK And Ireland)