Art-literature-journalism
- Maya Angelou (born 1928), author and poet
- Jabari Asim (born 1962), author, journalist
- Thomas P. Barnett (1870–1929), architect and impressionist painter
- Thomas Hart Benton (1889–1975), painter
- George Caleb Bingham (1811–1879) artist (born in Virginia but moved to central Missouri)
- Mark Bowden (born 1951), author, journalist
- William S. Burroughs (1914–1997), author
- Kate Chopin (1851–1904), author (The Awakening) and early Feminist
- Lester Dent (1904–1959), author Doc Savage novels
- Suzette Haden Elgin (born 1936), science fiction author and linguist
- T. S. Eliot (1888–1965), poet, dramatist and literary critic
- Lisa Myers (born 1951), journalist
- Mary Engelbreit (born 1952), graphic artist, children's book illustrator
- Michael Evans (1944—2005), photographer
- Eugene Field (1850–1895), writer and poet
- Martha Gellhorn (1908–1998), novelist, travel writer and journalist
- William Least Heat-Moon (born 1940), travel writer
- Robert A. Heinlein (1907–1988), science fiction author
- Langston Hughes (1902–1967), African-American poet, novelist and playwright
- William W. Johnstone (1938–2004), author of western, horror & survivalist novels
- Donald Judd (1928–1994), artist
- Jim Lee (born 1964), comic book artist and writer
- David Limbaugh (born 1952), columnist, author, political commentator
- Bernarr Macfadden (1868–1955), founder Macfadden Publications, bodybuilding advocate
- Mary Margaret McBride (1899–1976), female radio pioneer
- Dennis L. McKiernan (born 1932), author
- Russ Mitchell (born 1960), TV journalist, former CBS Evening News weekend anchor
- Marianne Moore (1887–1972), poet and writer
- Archie Musick (1902–1978), painter and illustrator, most associated with the Regionalist movement.
- John R. Musick (1849–1901), author and poet, best known for the Columbian Historical novels
- Ruth Ann Musick (1897–1974), author and folklorist
- Reinhold Niebuhr (1892–1971), author, theologian, political commentator
- Stone Phillips (born 1954), TV journalist and newsmagazine host (Dateline NBC)
- Joseph Pulitzer (1847–1911), journalist (from Hungary), known for creating St. Louis Post-Dispatch and the prestigious Pulitzer Prize
- John Ross (born 1957), author
- Charles Marion Russell (1864–1926), artist
- Clay Shirky (born 1964), writer, consultant, lecturer, author of Here Comes Everybody
- Kimora Lee Simmons, fashion model, author, actress
- Sara Teasdale (1884–1933), poet
- Mark Twain (real name Samuel Clemens, 1835–1910), humorist, writer and lecturer
- Verner Moore White (1863–1923), artist
- Laura Ingalls Wilder (1867–1957), writer and author of the Little House book series
- Tennessee Williams (1911–1983), playwright (born in Mississippi but grown up in St. Louis)
- Daniel Woodrell (born 1953), author of crime fiction
Read more about this topic: List Of People From Missouri