N
- Ajay Naidu, actor, Office Space, LateLine
- Suzy Nakamura, actress, Deep Impact, DodgeBall: A True Underdog Story, The 40-Year-Old Virgin
- Heather Nauert, news anchor for the Fox News Channel
- Baby Face Nelson, bank robber and murderer in the 1930s
- Karl Nelson, former offensive tackle for the New York Giants
- Michael J. Nelson, comedian and writer, Mike Nelson on Mystery Science Theater 3000
- Wayne Nelson, (born 1950) musician from classic rock's Little River Band
- Eliot Ness, Chief Investigator of the Prohibition Bureau
- Marisol Nichols, actress, Resurrection Blvd., 24, Blind Justice
- Nichelle Nichols, actress, Star Trek
- Alexa Nikolas, actress, Zoey 101, Hidden Hills
- Rob Ninkovich, linebacker and defensive end for the New England Patriots
- Ray Nitschke, Hall of Fame linebacker for the Green Bay Packers
- Frank Nitti, gangster
- Ken Norton, former heavyweight boxer
- Ken Norton, Jr., former NFL linebacker and current linebackers coach for the Seattle Seahawks
- Kim Novak, actress, Vertigo
- Robert Novak, syndicated columnist, journalist, TV personality, author, conservative political commentator
- Steve Novak, small forward and power forward for the New York Knicks
- Mike Nussbaum, actor, Men in Black
Read more about this topic: List Of People From Illinois