Norfolk
- Adam Anderson - driver of the Taz and Grave Digger Monster Trucks, and son of Monster Truck driver Dennis Anderson
- Dennis Anderson - driver of the Grave Digger Monster Truck in the monster truck series, Monster Jam
- Mason Andrews (1919–2006) – physician who delivered America's first in vitro baby, visionary leader of Norfolk's late 20th century renaissance
- Gordon Banks musician (b. 1955) - guitarist and music director for Marvin Gaye
- Al Barks (b. 1936) - Negro league baseball player
- Gary "U.S." Bonds (b. 1939) – singer and songwriter
- Plaxico Burress (b. 1977) – professional football wide receiver for the New York Jets
- William Harvey Carney (1840–1908) – African-American soldier of the American Civil War, Medal of Honor recipient for his part in the 54th Massachusetts Infantry's assault on Fort Wagner, South Carolina
- Clarence Clemons – saxophonist for Bruce Springsteen's E Street Band
- Alex Cosmidis – Minor League baseball player and manager and Major League scout
- William Couper (1853–1942) – Sculptor
- Colgate Whitehead Darden, Jr. (1897–1981) – U.S. Representative, Governor of Virginia, Chancellor of the College of William and Mary and the third President of the University of Virginia
- Charles "Lefty" Driesell (b. 1931) – famed basketball coach at Davidson University, the University of Maryland, College Park, James Madison University, and Georgia State University
- Rob Estes (b. 1963) – actor
- Samuel Face (1923–2001) – inventor
- William Fuller (b. 1962) – professional football defensive end for the Houston Oilers, Philadelphia Eagles and Chicago Bears
- Stephen Furst (b. 1954) – television actor
- Henry Howell (1920–97) – Independent Lieutenant Governor of Virginia
- General Norman Johnson (b. 1943) – R&B musician
- Kishi Bashi (b. 1975) – indie rock Violinist/Musician. Solo and tour member of of Montreal and Regina Spektor.
- Lawrence "LoJo" Johnson (b. 1974) - Olympic pole vaulter, silver medalist in 2000
- Naomi Long Madgett (b. 1923) – African American poet
- Mae – indie rock band
- Timothy "Timbaland" Mosely (b. 1971) – Hip hop artist and producer, longtime associate of Missy Elliott
- Ryan Farish (b. 1974) - music composer, artist, publisher, and record executive of Rytone Entertainment.
- Thomas W. Moss, Jr. (b. 1928) – Democratic Speaker of the Virginia House of Delegates, 1992–2000
- Wayne Newton (b. 1942) – a.k.a. "Mr. Las Vegas"; singer and songwriter
- Tim Reid (b. 1944) – television actor, director, and film executive
- Jodi Rell (b. 1946) – Republican Governor of Connecticut, 2004–2011
- Joseph Jenkins Roberts (1809–76) – First President of Liberia
- Larry Sabato (b. 1952) – National Political Pundit and Professor at the University of Virginia
- Bob Saget (b. 1956) – actor and comedian, current host of 1 vs. 100; best known for his role as Danny Tanner on the 1987-95 series Full House as well as the original host of America's Funniest Home Videos
- Ed Schultz (b. 1954) – pundit and TV personality for MSNBC
- Deborah Shelton (b. 1948) – actress; Miss USA 1970, 1st runner-up in Miss Universe contest
- John Wesley Shipp (b. 1956) – television actor
- Bruce Smith (b. 1963) – Pro Football Hall of Fame football player for the Buffalo Bills and Washington Redskins
- Joe Smith (b. 1975) – professional basketball player for the Philadelphia 76ers
- Keely Smith (b. 1932) – nightclub singer, wife and stage partner of Louis Prima
- Margaret Sullavan (1909–60) – actress and wife of Leland Hayward
- Chuck Swirsky - Chicago Bulls radio play-by-play announcer, previously with Toronto Raptors
- Littleton Waller Tazewell (1774–1860) – U.S. Representative, U.S. Senator and Governor of Virginia
- Scott Travis (b. 1961) – drummer for rock band Judas Priest
- John Paul Vann (1924–72) - U.S. soldier and civilian active in Vietnam
- Marc Vann (b. 1954) – actor
- Brandon Vera (b. 1977) – Mixed Martial Artist, currently signed to UFC
- Gene Vincent (1935–71) – rock-a-billy artist recorded the hit "Be-Bop-A-Lula"
- Ben Watson (b. 1980) – American Football player for the New England Patriots
- Ernie Watts (b. 1945) – composer, jazz saxophonist, and long-time touring member of The Rolling Stones
- Joe Weatherly (1922–64) – NASCAR driver
- Pernell "Sweet Pea" Whitaker (b. 1964) - boxer; 1984 Olympic gold medalist, professional champion in 4 weight classes
- Thomas Wilkins (b. 1954) – orchestra conductor, music director of the Omaha Symphony Orchestra
- Patrick Wilson (b. 1973) – actor
- David Wright (b. 1982) – professional baseball player for the New York Mets.
Read more about this topic: List Of People From Hampton Roads