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- William Temple (1814–1863), Governor and U.S. Representative from Delaware
- Charles L. Terry, Jr. (1900–1970), Chief Justice and Governor of Delaware
- William Tharp (1803–1865), General Assembly and as Governor of Delaware
- Charles Thomas (1790–1848), General Assembly and Governor of Delaware
- Lorenzo Thomas, (1804-18750), United States Army Adjunct General, participant in the impeachment trial of Andrew Johnson
- Sean Patrick Thomas (born 1970), actor; born in Wilmington
- Jim Thompson (born 1906), businessman; born in Greenville
- George Thorogood (born 1951), blues-rock musician; from Wilmington
- James Tilton (1745–1822), physician, soldier, delegate in the Continental Congress; from Dover
- Alfred Thomas Archimedes Torbert (1833–1880); Union Army General and U.S. diplomat; born in Georgetown
- Reorus Torkillus (1608–1643), first Swedish Lutheran Minister to New Sweden
- John G. Townsend, Jr. (1871–1964), Governor and U. S. Senator from Delaware
- Philip A. Traynor (1874–1962), dentist and U.S. Representative from Delaware
- Sherman W. Tribbitt (born 1922), Lieutenant Governor and Governor of Delaware
- George Truitt (1756–1818), General Assembly and Governor of Delaware
- Ebe W. Tunnell (1844–1917), General Assembly and Governor of Delaware
- James M. Tunnell (1879–1957), lawyer and U.S. Senator from Delaware
Read more about this topic: List Of People From Delaware