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- Connie Ediss, buxom comedienne in Edwardian music hall, also acted in a few 1930s films, born and died in Brighton
- Les Edwards, illustrator, lives in Brighton
- Nick Van Eede, lead singer, Cutting Crew
- Adam El-Abd, Egyptian-English footballer for Brighton & Hove Albion, was born in Brighton in 1984
- Jago Eliot, Lord Eliot, involved in a variety of arts projects, briefly lived in Brighton
- Charlotte Elliott, poet and hymn writer, lived in Brighton in the latter part of her life
- G. H. Elliott, music hall singer and comedian, buried in Rottingdean church yard
- Sean Ellis, film director, was born in Brighton c.1970
- Steve Ellis, singer with the band Love Affair, lives in Brighton
- Bella Emberg, actress; co-star of The Russ Abbot Show
- Revd. Richard Enraght, religious controversialist, curate of St. Paul's Church, Brighton 1867–71, and priest in Charge of St. Andrew's Church, Portslade 1871–74
- Chris Eubank, ex-boxer, who holds the purchased title of "Lord of the Manor of Brighton"
- Chris Eubank, Jr., boxer, son of Chris Eubank, lives in Brighton
- Maurice Evans, leading Shakespearan actor in the United States, regularly in Bewitched and Batman, and Dr Zaius in Planet of the Apes
- Simon Evans, comedian, lives in Hove
- George Everest, surveyor after whom the mountain was named, buried in Hove
- Marjorie Eyre, D'Oyly Carte soprano, died in Brighton in 1987
Read more about this topic: List Of People From Brighton And Hove