South America
- 1819 - Gran Colombia (Greater Colombia) is created from New Granada, the Royal Audience of Quito, and former Spanish territories, composed of modern day Colombia, Ecuador, Panama, and Venezuela and other territories.
- 1831 - Gran Colombia is dissolved and the following states are created: the Republic of the New Granada (Colombia), Ecuador, and Venezuela.
- 1836 - 1839 - The War of the Confederation which is fought between the recently formed Peru-Bolivian Confederation versus Chile and its ally Argentina as well as anti-confederate Peruvians. The war ends with Chile winning the war and the re-creation of the separate states of Peru and Bolivia.
- 1899 - 1900 - the breakway state of the Republic of Acre is formed after Acre (state) separates from Bolivia; annexed by Brazil three years later.
- 1903 - Panama separates from Colombia.
Read more about this topic: List Of National Border Changes From 1815 To 1914
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