M
- William C. Macdonald – tobacco manufacturer, philanthropist
- Danny Maciocia – CFL football coach
- Nicolas Macrozonaris – sprinter, Canadian track and field
- Don Macpherson – journalist
- Arnaud Maggs – artist, photographer
- Jeanne Mance – founder of first hospital in North America, l'Hôtel-Dieu de Montréal, 1645
- Rudolph A. Marcus –, Nobel laureate of chemistry
- Lou Marinoff – philosopher at City college of New York
- Yann Martel – writer, Man Booker Prize 2002
- Paul Martin – former Prime Minister of Canada
- Russell Martin – baseball player for the New York Yankees
- Massari – singer
- Diego G. Mazzone – sales management professional
- John McCallum – politician
- John Wilson McConnell – businessman, publisher, philanthropist
- David Ross McCord – lawyer, philanthropist
- Kevin McDonald – actor/comedian/voice actor, member of The Kids in the Hall
- Thomas D'Arcy McGee – politician
- Duncan McIntyre – businessman
- Scott McKay – former city counsellor and leader of the Green Party of Quebec
- Patricia McKenzie – actress
- Norman McLaren – film animation pioneer
- Simon McTavish – businessman
- Juan Mendez – former NCAA basketball player, Niagara University
- Charles Meredith – president of the Montreal Stock Exchange
- Frederick Edmund Meredith – lawyer, chancellor of Bishop's University
- Vincent Meredith – 1st and last Baronet of Montreal, President of the Bank of Montreal
- William Collis Meredith – Chief Justice of the Superior Court of Quebec
- Luck Mervil – singer, actor
- Brenda Milner – neuropsychologist
- Hartland Molson – brewer, World War II fighter pilot, statesman
- John Molson – brewer, railway and steamship line builder
- Percival Molson – athlete, soldier
- Édouard Montpetit – lawyer, economist, academic
- Henry Morgan – department store founder
- Henry Morgentaler – physician, advocate for women's rights to abortion
- Terry Mosher – editorial cartoonist
- Emilie Mover – singer
- Ben Mulroney – Canadian television host, son of Brian Mulroney
- Brian Mulroney – former Prime Minister of Canada
- Mila Mulroney – wife of the 18th Prime Minister of Canada, Brian Mulroney
Read more about this topic: List Of Montreal Athletes