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- John Calipari, basketball coach
- Dolph Camilli, baseball player
- Roy Campanella, baseball player
- Lou Campi, bowler
- Tony Canadeo, football player
- Tony Canzoneri, boxer
- Donna Caponi, LPGA golfer
- Gino Cappelletti, football player
- Harry Caray, baseball commentator
- Frankie Carideo, football player
- Primo Carnera, boxer and wrestler
- Lou Carnesecca, basketball coach
- Santo Catanzaro
- Phil Cavarretta, baseball player
- Al Cervi, basketball player and coach
- Giorgio Chinaglia, soccer player
- Dino Ciccarelli, hockey player
- Jerry Colangelo, basketball executive
- Rocky Colavito, baseball player
- Frank Coltiletti, jockey
- Franco Columbu, bodybuilder
- Tony Conigliaro, Major League Baseball Player
- John Conti
- Young Corbett III, boxer
- Jim Covert, football player
- Frank Crosetti, baseball shortstop
- Tony Cuccinello, baseball player
- Pete Cutino, water polo coach
- Bobby Czyz, boxer
Read more about this topic: List Of Members Of The Italian American Sports Hall Of Fame