S
- Amir Sadollah – (UFC)
- Tarec Saffiedine – (DREAM, Strikeforce)
- Alessio Sakara – (MFC, UFC)
- Kazushi "Gracie Hunter" Sakuraba – (K-1 HERO'S, PRIDE, UFC, DREAM)
- Hayato Sakurai – (DEEP, PRIDE, Shooto, UFC, DREAM)
- Ivan Salaverry – (K-1, Shooto, UFC, WFA)
- Sean Salmon – (UFC)
- Diego Sanchez – (KOTC, UFC)
- Jorge Santiago – (UFC, Strikeforce, World Victory Road)
- Evangelista Santos – (Cage Rage, Pancrase, PRIDE, World Victory Road)
- Rey-Phillip Santos – (IFC, Pancrase)
- Bob Sapp – (K-1, K-1 HERO'S, PRIDE, DREAM)
- Rumina Sato – (Shooto)
- Kerry Schall – (UFC)
- Nino Schembri – (PRIDE)
- Fabiano Scherner – (UFC, Cage Rage, IFL)
- Semmy Schilt – (K-1 HERO'S, Pancrase, PRIDE, UFC)
- Alex Schoenauer – (IFL)
- Ryan Schultz – (IFL, World Victory Road)
- Pete Sell – (UFC)
- Andrei Semenov – (BodogFIGHT, M-1)
- Ivan Serati – (Cage Rage)
- Matt Serra – (UFC)
- Nick Serra – (UFC)
- Dan "The Beast" Severn – (KOTC, PRIDE, UFC, WEC)
- Frank Shamrock – (K-1, Pancrase, Strikeforce, UFC, WEC)
- Ken Shamrock – (Pancrase, PRIDE, UFC)
- Sean Sherk – (KOTC, PRIDE, UFC)
- Katsuyori Shibata – (K-1 HERO'S)
- Jake Shields – (BodogFIGHT, Elite XC, Pancrase, Shooto, Strikeforce, UFC)
- Akira Shoji – (Cage Rage, DEEP, KOTC, Pancrase, PRIDE)
- Anderson Silva – (Cage Rage, PRIDE, Shooto, UFC)
- Antonio Silva – (K-1 HERO'S, EliteXC, World Victory Road, Strikeforce)
- Assuerio Silva – (Pancrase, UFC)
- Erick Silva – (Jungle Fight, UFC)
- Paulo Silva – (K-1 HERO'S, PRIDE)
- Jay Silva – (UFC)
- Jean Silva – (Cage Rage, PRIDE)
- Thiago Silva – (Pancrase, Shooto, UFC)
- Wanderlei Silva – (PRIDE, UFC)
- Marcus Silveira – (UFC)
- Aaron Simpson – (UFC, WEC)
- Wes Sims – (IFL, UFC)
- Rob Sinclair – (BAMMA)
- Rory Singer – (PRIDE, UFC)
- Elvis Sinosic – (Cage Rage, Pancrase, UFC)
- Dennis Siver – (UFC)
- Jimmy Smith – (KOTC, Pangea)
- Maurice "Mo" Smith – (IFL, Pancrase, PRIDE, UFC)
- Patrick Smith – (K-1, UFC)
- Scott Smith – (UFC, WEC, EliteXC)
- Renato "Babalu" Sobral – (Cage Rage, Affliction, Strikeforce, UFC)
- Rameau Thierry Sokoudjou – (PRIDE, WEC, UFC, Affliction)
- Joe Son – (PRIDE, UFC)
- Chael Sonnen (Team Quest, WEC, UFC)
- Krzysztof Soszynski – (IFL, Strikeforce, TKO, UFC)
- George Sotiropoulos – (UFC)
- Ronaldo de Souza
- Ron Sparks – (KOTC, K-1, Strikeforce)
- Mario Sperry – (Cage Rage, PRIDE)
- Pete Spratt – (TKO, UFC)
- Brian Stann – (WEC, UFC)
- Aaron Stark – (IFL)
- Kalib Starnes – (UFC, Destiny)
- Joe Stevenson – (KOTC, UFC)
- Luke Stewart – (Strikeforce)
- Denis Stojnic – (UFC)
- Curtis Stout – (Cage Rage, MFC, TKO, UFC)
- Sam Stout – (TKO, UFC)
- Georges St-Pierre – (TKO, UFC)
- Stefan Struve – (UFC)
- Genki Sudo – (K-1, K-1 HERO'S, Pancrase, UFC)
- Amar Suloev – (M-1, Pancrase, PRIDE FC, UFC)
- Magomed "White Wolf" Sultanakhmedov – (Dream, K-1, M-1)
- Mike Swick – (UFC, WEC)
- Takashi Sugiura – (Pancrase, PRIDE)
- Minoru Suzuki – (DEEP, Pancrase)
- Tim Sylvia – (UFC, Affliction)
Read more about this topic: List Of Male Mixed Martial Artists