Single-season
| Inducted into the National Baseball Hall of Fame and Museum | |
| § | Active player |
| Player | Home runs | Season total | Year | Team | Ref |
|---|---|---|---|---|---|
| Ferrell, WesWes Ferrell | 9 | 9 | 1931 | Cleveland Indians | |
| Stivetts, JackJack Stivetts | 7 | 7 | 1890 | St. Louis Browns | |
| Ferrell, WesWes Ferrell | 7 | 7 | 1933 | Cleveland Indians | |
| Lemon, BobBob Lemon | 7 | 7 | 1949 | Cleveland Indians | |
| Newcombe, DonDon Newcombe | 7 | 7 | 1955 | Brooklyn Dodgers | |
| Drysdale, DonDon Drysdale | 7 | 7 | 1958 | Los Angeles Dodgers | |
| Drysdale, DonDon Drysdale | 7 | 7 | 1965 | Los Angeles Dodgers | |
| Wilson, EarlEarl Wilson | 7 | 7 | 1968 | Detroit Tigers | |
| Hampton, MikeMike Hampton | 7 | 7 | 2001 | Colorado Rockies | |
| Clarkson, JohnJohn Clarkson | 6 | 6 | 1887 | Chicago White Stockings | |
| Hutchinson, BillBill Hutchinson | 6 | 6 | 1894 | Chicago Colts | |
| Schumacher, HalHal Schumacher | 6 | 6 | 1934 | New York Giants | |
| Ferrell, WesWes Ferrell | 6 | 7 | 1935 | Boston Red Sox | |
| Harshman, JackJack Harshman | 6 | 6 | 1956 | Chicago White Sox | |
| Harshman, JackJack Harshman | 6 | 6 | 1958 | Baltimore Orioles | |
| Wilson, EarlEarl Wilson | 6 | 6 | 1965 | Boston Red Sox | |
| Wilson, EarlEarl Wilson | 6 | 7 | 1965 | Boston Red Sox/Detroit Tigers | |
| Jenkins, FergusonFerguson Jenkins | 6 | 6 | 1971 | Chicago Cubs | |
| Siebert, SonnySonny Siebert | 6 | 6 | 1971 | Boston Red Sox | |
| Wise, RickRick Wise | 6 | 6 | 1971 | Philadelphia Phillies | |
| Zambrano, CarlosCarlos Zambrano§ | 6 | 6 | 2006 | Chicago Cubs |
Read more about this topic: List Of Major League Baseball All-time Leaders In Home Runs By Pitchers