Souphanousinphones
- Kahn Souphanousinphone, Sr. (voiced by Toby Huss) — Kahn is Hank's antagonistic, sardonic, acerbic, materialistic, arrogant, Laotian next-door neighbor. "Kahn" is an anagram of "Hank". He believes he is better than his neighbors, often referring to them as "hillbillies" or "rednecks." He frequently boasts his superiority to the others, but Hank bails him out in several episodes, and Kahn has made it clear that he strongly respects Hank (though he also has made it clear this respect does not extend to Bill, Boomhauer, and especially Dale). Upon recollection of the story of how Minh and Kahn met, it is revealed that he was a former rebel and playboy whom Minh chose over the straight-laced intellectual her father set her up with. In one episode Kahn shows that he is a trained martial artist while getting into a fight with a few rednecks. Kahn also occasionally wrestles with the fact that he has a daughter, and once, when very angry with her when she said she wanted to quit the school wrestling team, stated, "You lose, you no longer my son!" His license plate has the words "King Kahn" on it, which parodies King Kong. In the episode "Just Another Manic Kahn-Day", it is revealed that Kahn has bipolar disorder (likely bipolar I disorder). It is revealed in the episode "Three Days of the Kahndo" that Kahn has a brother also living in the US with a family of his own. The same episode establishes that Kahn's home was previously occupied for 13 years by a man named Dave Henson, a 500-lb. shut-in who had to be removed by cutting a hole through the outer wall when he moved out.
- Minh Souphanousinphone (voiced by Lauren Tom) — Kahn's wife. Minh is a housewife who enjoys making extremely rude comments about the neighbors, particularly Peggy. She sometimes has disapproving, offensive, snobbish attitude toward the neighbors, but in reality, she is a more understanding parent and a better neighbor than Kahn, which often allows her to connect with Connie in a way her dad never could (as seen in "Father of the Bribe"). She also has a fondness for adding nutmeg to everything she cooks to make it taste better. She's a crack shot, with championship-level skills, and at one point joined Dale's gun club, exerting a positive effect on its members. She is highly competitive, going so far as to cheat on The New York Times crossword puzzle. Like her husband, Minh grew up in Laos, where her father was a powerful general in the army who was not happy with her decision to marry Kahn. She also unsuccessfully tried to teach Bobby Lao.
- Kahn "Connie" Souphanousinphone, Jr. (voiced by Lauren Tom) — Connie is the daughter of Kahn and Minh, and one of Bobby's best friends and his ex-girlfriend. She is a violin player, "A" student, and general overachiever pressured by her mother and father, who hold her to very high standards. Though it is implied that she works hard because of her overbearing parents, in reality, she does it for herself, which, according to her, is the product of a deep psychological compulsion she cannot explain. She reveals to Bobby that she has a secret desire to physically assault and/or harm her father. Connie is named after her father because he wanted a son.
- Doggie Kahn — Doggie Kahn (often referred to simply as "Doggie") is their West Highland White Terrier, who has the uncanny ability to turn backflips, and is a competitive dancer. He once ran away with Ladybird. His name is a play on "Donkey Kong."
- Tid Pao Souphanousinphone (voiced by Lucy Liu) — Tid Pao is Connie's criminally-inclined cousin from Los Angeles and the main antagonist in "Bad Girls, Bad Girls, Whatcha Gonna Do", who was sent to stay at Kahn's for a semester because she stole drugs from a street gang. She attended Tom Landry Middle School in the meantime. She seduced Bobby and tricked him into creating a meth lab by pretending to help him with building a candy machine for his group science project, and persuaded him to steal propane tanks from Strickland Propane to complete it. Upon seeing a policeman grading projects during the science fair, she told Bobby he could take all the credit and ran off. Connie saved him by shooting the lab to pieces with a spud gun. Tid Pao was sent away by Kahn to Wisconsin to work on her last uncle's dairy farm at the end of the episode because of her criminally-inclined nature. She was also warned by her last uncle that she would be sent back to her grandmother in Laos if she misbehaved again.
- Laoma Souphanousinphone (voiced by Amy Hill) — Laoma is Kahn's mother and the only person on the show who addresses him by his full name (Kohng Koy Kahn Souphanousinphone). She is kind and hardworking and thoroughly enjoys housekeeping. She is disliked by Minh because of her criticism of Minh's housework skills. The status conscious Kahn is horrified when Laoma, bored and unwanted by her daughter-in-law, becomes the Hills' housemaid, and even more horrified when she begins a love affair with Bill Dauterive. Laoma is briefly mentioned in the following episode "The Witches of East Arlen," but is not seen. After this there was no mention of their relationship, nor has Laoma herself been seen since her first episode, mainly because the creators nixed the original plan for her and Bill to become a regular couple, preferring for Bill to remain his usual single and miserable self. Although she doesn't appear in later episodes, it is implied in a later episode that she gave household tips to Minh via phone, to give to Peggy in exchange for New York Times Crossword Puzzle answers. She was born in a poor village in Laos.
- Gen. Gum (voiced by James Sie) — Usually referred to as "The General," (his full name is Gum Nga Hexumalayasabrath) he appeared only in the episodes "Pour Some Sugar on Kahn" (in which he visits the family) and "Father of the Bribe" (in which Minh recalls her courtship by Kahn). He is Minh's father and greatly dislikes Kahn. He served under several Laotian dictators and was put on trial for war crimes at The Hague. While he constantly ordered Kahn to do his errands, he grew angry as Kahn gained confidence from karaoke and started to stand up to him. After singing Kahn's favorite song, he quickly regained dominance over his son-in-law. Kahn became very depressed, forcing Minh to confront her father about his treatment of her husband. As a result, The General struck a deal with Kahn, in which he would leave if Kahn admitted The General was his superior in every way. Before leaving, the general offered Kahn a small amount of praise, but still refused to shake his hand.
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