C
- Chessmen - Chess-themed henchmen of Obadiah Stane.
- Coldblood - Lieutenant Colonel going by the real name of Eric Savin. Resurrected as a Cyborg after having Cyberbenetic surgery.
- Controller - A power hungry scientist with the expertise to control minds.
- Count Nefaria - Leader of the crime cartel the Maggia.
- Crimson Cowl - The daughter of Justin Hammer later used the identity to lead a team of Masters of Evil and bedevil the Thunderbolts.
- Crimson Dynamo - A Soviet supersoldier clad in powered armor.
- Crusher I - A South American scientist who created the "Crusher 1" Formula which granted him with super-strength, dense skin, and a weight of 1,000 lb (450 kg).
Read more about this topic: List Of Iron Man Enemies