D
- Decapitron (Puppet Master 4 and its sequels) - Guy Rolfe
- Divoletto (Demonic Toys 2)
- Jerry Dandrige (Fright Night) - Chris Sarandon (Colin Farrell in the 2011 remake)
- David (The Lost Boys) - Kiefer Sutherland
- Death (Final Destination)
- Gerald Demus (Resurrection) - Robert Joy
- Ben and Gary Dexter (Captivity) - Pruitt Taylor Vince and Daniel Gillies
- Diamondback (Near Dark) - Jenette Goldstein
- Matilda Dixon (Darkness Falls)
- Nathaniel Demerest (Wishmaster) - Andrew Divoff
- John Doe (Se7en) – Kevin Spacey
- The Dogs (The Breed)
- Francis Dolarhyde (Manhunter) - Tom Noonan
- Francis Dolarhyde (Red Dragon (film))- Ralph Fiennes
- The Dolls (Dolls)
- The Dolls (Dolly Dearest)
- Dolly (Dolly Dearest)
- Otis B. Driftwood (House of 1000 Corpses) - Bill Moseley
- The Driller Killer (Slumber Party Massacre II ) - Atanas Ilitch
- Curt Duncan (When a Stranger Calls) - Tony Beckley
- Dwayne (The Lost Boys) - Billy Wirth
Read more about this topic: List Of Horror Film Antagonists