C
- Richard "Ricky" Caldwell (Silent Night, Deadly Night Part 2) - Eric Freeman
- David Callaway (Hide and Seek) - Robert De Niro
- Caller (Phone Booth) - Kiefer Sutherland
- Camilla (The Guardian) - Jenny Seagrove
- Hedy Carlson and Ellen Besch (Single White Female) - Jennifer Jason Leigh
- Ray Carlton (He Knows You're Alone) - Tom Rolfing
- Simon Cartwright (The Ugly) - Paolo Rotondo
- William "Billy" Chapman (Silent Night, Deadly Night) - Robert Brian Wilson
- Chatterer (Hellraiser and eight sequels) - Nicholas Vince
- Jennifer Check (Jennifer's Body) - Megan Fox
- Children of the Corn (Children of the Corn, seven sequels and one remake)
- Christine (Christine)
- Santa Claus (Santa's Slay) - Bill Goldberg
- Royce Clayton (Thirteen Ghosts)
- Ezra Cobb (Deranged) - Roberts Blossom
- Conal Cochran (Halloween III: Season of the Witch) - Dan O'Herlihy
- Coffin Baby (Toolbox Murders) - Christopher Doyle
- Billy Cole (Fright Night) - Jonathan Stark
- Matthew Cordell (Maniac Cop) - Robert Z'Dar
- Elizabeth Craven (The Tooth Fairy)
- Thomas Cray (Nightwatch) – Nick Nolte
- Gage Creed (Pet Sematary) - Miko Hughes
- Creeper (Jeepers Creepers and its 2003 sequel) - Jonathan Breck
- Crocodile (Lake Placid and two sequels)
- Cropsy (The Burning) - Lou David
- Victor Crowley (Hatchet) - Kane Hodder
- Cujo (Cujo)
- Cult of Thorn (Halloween: The Curse of Michael Myers)
- Stanley Cunningham (Camp Blood and its 2000 sequel)
- Carlino (Wait Until Dark) - Jack Weston
Read more about this topic: List Of Horror Film Antagonists