S
- Sacré Cœur School
- Sacred Heart College, Oakleigh
- Sacred Heart Girls' College
- Salesian College
- Samaritan Catholic College
- Sandringham College
- Santa Maria College
- Scoresby Secondary College
- Scotch College, Melbourne
- Shelford Anglican Girls' School
- Shelford Girls Grammar School
- Sherbrooke Community School
- Siena College, Melbourne
- Simonds Catholic College, West Melbourne
- South Oakleigh Secondary College
- Sophia Mundi Steiner School
- Southwood Boys' Grammar School
- Springvale Secondary College
- St Albans Secondary College
- St Aloysius' College
- St Andrew's Christian College
- St Anthony's Coptic Orthodox College
- St Bede's College (Mentone)
- St. Bernard's College, Melbourne
- St Catherine's School, Toorak
- St. Columba's College, Melbourne
- St Francis Xavier College, Melbourne
- St Helena Secondary College
- St John's Greek Orthodox College
- St John's Regional College
- St. Joseph's College, Melbourne
- St. Joseph's College, Ferntree Gully
- St. Kevin's College, Melbourne
- St Leonards College
- St Margaret's School, Melbourne
- St Mary's Coptic Orthodox College
- St Michael's Grammar School
- St Monica's College
- St Paul's Anglican Grammar School
- St. Paul's College, Melbourne
- St Peter's College, Cranbourne
- St Thomas Aquinas College
- Star of the Sea College
- Staughton College
- Stott's College
- Strathcona Baptist Girls' Grammar School
- Strathmore Secondary College
- Sunbury College
- Sunbury Downs Secondary College
- Sunshine College
- Swinburne Senior Secondary College
- Sydney Road Community School
Read more about this topic: List Of High Schools In Melbourne