F
- Falcon in Captain America #117
- Fantomex in New X-Men #128
- Fandral in Journey into Mystery #119
- Fantasti-Car in Fantastic Four #3
- Fantastic Four in Fantastic Four #1
- Feral in New Mutants #99
- Fin Fang Foom in Strange Tales #89
- Firebird in Incredible Hulk #265
- Firelord in Thor #225
- Firestar (TV first appearance)
- Spider-Man and His Amazing Friends, episode 1: "The Triumph of the Green Goblin" (original airdate: December 1981)
- in comics: Spider-Man and His Amazing Friends #1, December 1981
- Foolkiller in Foolkiller #1
- Forge in Uncanny X-Men #184
- Forgotten One in The Eternals #13
- Franklin Richards in Fantastic Four Annual #6
Read more about this topic: List Of First Appearances In Marvel Comics Publications