D
- Dagger in The Spectacular Spider-Man #64
- Damage Control in Marvel Comics Presents #19
- Daredevil in Daredevil #1
- Dark Angel in Hell's Angel #1
- Darkhawk in Darkhawk #1
- Darkhold Redeemers in Darkhold #1
- Dazzler in Uncanny X-Men #130, February 1980
- Deadpool in New Mutants #98
- Deadzone in Moon Knight #47
- Deathbird in Ms. Marvel #9
- Deathwatch in Ghost Rider Vol.2 #1
- Death's Head in Dragon's Claws #5
- Death Metal in Death3 #1
- Defenders in Marvel Feature #1*Demogoblin in Web of Spider-Man #86
- Destiny
- as Paul Destine (behind the scenes) in Tales to Astonish #101; (actual) in Iron Man and Sub-Mariner #1, April 1968
- as a Marvel Comics personification in Marvel Two-in-One #6, November 1974
- as Irene Adler in Uncanny X-Men #141, January 1981
- Destroyer
- Golden Age hero: Mystic Comics #6, October 1941
- Marvel Comics villain: Strange Tales #101, October 1962
- Thor character: Journey into Mystery #118, July 1965
- Deviants in The Eternals #1
- Diablo in Fantastic Four #30
- Die-Cut in Deaths Head & Die Cut #1
- Dire Wraith in ROM #1
- Doc Samson in Incredible Hulk #141
- Doctor Doom in Fantastic Four #5
- Doctor Druid in Amazing Adventures #1
- Doctor Octopus in The Amazing Spider-Man #3
- Doctor Strange in Strange Tales #110
- Domino in New Mutants #98
- Dormammu in Strange Tales #126
- Dracula in Tomb of Dracula #1
- Dragon Man in Fantastic Four #35
- Drax the Destroyer in Iron Man #55
- Dreadnought in Strange Tales #154
- D'Spayre in Marvel Team-Up #68
Read more about this topic: List Of First Appearances In Marvel Comics Publications