S
- Lori S. (Acid King)
- Sabrina Sabrok
- Jonna Sailon (All Ends)
- Jenna Sanz-Agero (Vixen)
- Sandy Saraya (Saraya)
- Kitty Saric (Decadence)
- Cristina Scabbia (Lacuna Coil)
- Sonya Scarlet (Theatres des Vampires)
- Elizabeth Schall (Dreaming Dead)
- Inga Scharf (Van Canto)
- Sabine Scherer (Deadlock)
- Sandra Schleret (Dreams of Sanity, Eyes of Eden, Elis, Sigfried)
- Sever (Sumo Cyco)
- Otep Shamaya (Otep)
- Heather Shockley (Rock Ignition)
- Elena Siegman (Treyarch)
- Nell Sigland (The Crest, Theatre of Tragedy)
- Simone Simons (Epica, Aina, Kamelot, Ayreon)
- Maria Sjöholm (Drain STH)
- Vivian Slaughter (Gallhammer, Sehnsucht)
- Jada Pinkett Smith (Wicked Wisdom)
- Carly Smithson (We Are the Fallen)
- Amanda Somerville (Aina, HDK, Trillium)
- Donita Sparks (L7, Donita Sparks and the Stellar Moments)
- Eva Spence (Rolo Tomassi)
- Vibeke Stene (Tristania)
- Magdalena "Medeah" Stupkiewicz-Dobosz (Artrosis)
- Lacey Sturm (Flyleaf)
Read more about this topic: List Of Female Heavy Metal Singers