This is a list of the European Music & Media magazine's European Hot 100 Singles and European Top 100 Albums number-ones of 2000.
| Issue Date | Song | Artist | Album | Artist |
|---|---|---|---|---|
| 1 January | "If I Could Turn Back the Hands of Time" | R. Kelly | All the Way...A Decade of Song | Celine Dion |
| 8 January | ||||
| 15 January | ||||
| 22 January | "Move Your Body" | Eiffel 65 | ||
| 29 January | ||||
| 5 February | ||||
| 12 February | Supernatural | Santana | ||
| 19 February | ||||
| 26 February | ||||
| 4 March | ||||
| 11 March | "Sex Bomb" | Tom Jones & Mousse T. | ||
| 18 March | "American Pie" | Madonna | ||
| 25 March | ||||
| 1 April | ||||
| 8 April | ||||
| 15 April | ||||
| 22 April | ||||
| 29 April | ||||
| 6 May | "Maria Maria" | Santana featuring The Product G&B | ||
| 13 May | "Oops!...I Did It Again" | Britney Spears | ||
| 20 May | ||||
| 27 May | ||||
| 3 June | Oops!...I Did It Again | Britney Spears | ||
| 10 June | ||||
| 17 June | Crush | Bon Jovi | ||
| 24 June | "It's My Life" | Bon Jovi | ||
| 1 July | ||||
| 8 July | ||||
| 15 July | ||||
| 22 July | "The Real Slim Shady" | Eminem | ||
| 29 July | ||||
| 5 August | In Blue | The Corrs | ||
| 12 August | "Freestyler" | Bomfunk MC's | ||
| 19 August | "I'm Outta Love" | Anastacia | ||
| 26 August | ||||
| 2 September | "Lucky" | Britney Spears | ||
| 9 September | "Music" | Madonna | ||
| 16 September | ||||
| 23 September | ||||
| 30 September | ||||
| 7 October | Music | Madonna | ||
| 14 October | ||||
| 21 October | "Could I Have This Kiss Forever" | Whitney Houston & Enrique Iglesias | ||
| 28 October | "Beautiful Day" | U2 | ||
| 4 November | Chocolate Starfish and the Hotdog Flavored Water | Limp Bizkit | ||
| 11 November | "Lady (Hear Me Tonight)" | Modjo | Sailing to Philadelphia | Mark Knopfler |
| 18 November | All That You Can't Leave Behind | U2 | ||
| 25 November | "Shape of My Heart" | Backstreet Boys | ||
| 2 December | "One More Time" | Daft Punk | ||
| 9 December | "Independent Women Part I" | Destiny's Child | 1 | The Beatles |
| 16 December | ||||
| 23 December | "Stan" | Eminem featuring Dido | ||
| 30 December |
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