| Language | Comments | No. Speakers | Source | ISO 639-3 | Ethnologue entry |
|---|---|---|---|---|---|
| Ache language | Red Book | yif | Ache language | ||
| Angaite language | Red Book | ||||
| Ava-Guarani language | Red Book | ||||
| Ayoreo language | Red Book | ayo | Ayoreo language | ||
| Enlhet language | Red Book | ||||
| Guana language | Red Book | ||||
| Guarani-Nandeva language | Red Book | ||||
| Guarayo language | Red Book | ||||
| Ishir language | Red Book | ||||
| Maka language | Red Book | ||||
| Manjui language | Red Book | ||||
| Mbya language | Red Book | ||||
| Nivacle language | Red Book | cag | Nivacle language | ||
| Pai-Tavytera language | Red Book | ||||
| Sanapana language | Red Book | sap | Sanapana language | ||
| Toba-Maskoy language | Red Book | tmf | Toba-Maskoy language | ||
| Toba-Qom language | Red Book |
Read more about this topic: List Of Endangered Languages In South America