S
- Smokin' Aces (2007). Cocaine.
- The Salton Sea (2002). Methamphetamine.
- Sample People (1999). Fictional drug "glow" and cocaine.
- Savage Beach (1989). Heroin.
- Saving Grace (2000). Cannabis.
- A Scanner Darkly (2006). Cocaine, cannabis, and Substance D, a fictional psychoactive stimulant.
- Scarface (1983). Cocaine, heroin, Quaaludes.
- Scott Pilgrim Vs. The World (2010). Cannabis, mushrooms.
- Secrets of Chinatown (1935). Opium.
- The Serpent and the Rainbow (1988). Haitian witch concoction containing scopolamine.
- The Seven-Per-Cent Solution (1976). Cocaine.
- Sex & Drugs & Rock & Roll (2010). Cannabis, amphetamines, cocaine.
- Sex and the City (2008) Marijuana.
- The Sexy Killer (1976). Heroin.
- Shank (2010). Khat, Cannabis.
- Sherrybaby (2004). Heroin.
- She Shoulda Said 'No'! (1949). Cannabis.
- Shot List (2009). LSD, cocaine, cannabis.
- Shrooms (2007). Magic mushrooms, cannabis.
- Shrink (2009). Cannabis, amphetamine, cocaine.
- Siberia (1998). Cannabis, MDMA, amyl nitrate.
- Sid and Nancy (1986). Heroin, Methadone, cannabis.
- Skidoo (1968). LSD.
- Slackers (2002). Cannabis.
- SLC Punk! (1999). LSD, oxycodone, Perocet, cannabis.
- Sleepaway Camp II: Unhappy Campers (1988). Marijuana.
- Slim Susie (2003). Amphetamine, heroin, cannabis.
- Smiley Face (2007). Cannabis.
- Something Weird (1967). LSD
- Sorted (2000). Heroin, MDMA, Methamphetamine, Pills.
- Soul Plane (2004). Mushrooms, cannabis.
- Southwest Nine (2004). LSD, MDMA, cannabis.
- Spring Break (1983) Marijuana.
- Spun (2002). Methamphetamine.
- Squeeze (1997)
- Starsky & Hutch (2004). Cocaine.
- State Property (2002). Cannabis, crack/cocaine.
- Stark Raving Mad (2002). Cannabis, GHB, MDMA.
- Steal This Movie (2000). Cannabis.
- Steppenwolf (1974)
- Steve-O: Demise And Rise Cannabis, LSD, PCP, Cocaine, Nitrous Oxide, Pills, A lot
- Strange Days (1995) SQUID (fictional).
- Streets of Blood (2009). Cocaine/Crack
- Stripes (1981). LSD
- Stoned (2005). Cannabis, hachis, LSD, DMT, psilocybin, cocaine, alcohol, amphetamines, barbiturates.
- The Stoned Age (1994). Cannabis.
- Stoned: In The Beginning (2010). Cannabis, LSD, Cocaine, Sleeping Pills, Crack.
- Strange Wilderness (2008). Cannabis, nitrous oxide.
- The Student Nurses (1970) LSD.
- S.W.A.T FireFight (2011). Cannabis
- Summer of Sam (1999). Cocaine, cannabis.
- Sugarhouse (2007). Cannabis, Crack/Cocaine.
- Superbad (2007). Cocaine, cannabis.
- Super Fly (1972). Cocaine, cannabis.
- Super High Me (2007). Cannabis.
- Super Troopers (2001). Cannabis, psychedelic mushrooms, LSD.
- Surfer, Dude (2008). Cannabis.
- Synanon (1965). Heroin.
- Sweet Bird of Youth (1962). Amphetamine, cannabis (resin).
- Sweet Nothing (1996). Crack-Cocaine.
Read more about this topic: List Of Drug Films