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- La Haine (1995). Marijuana, Hashish, Cocaine.
- Lammbock (2001). Marijuana, hashish, psychedelic mushrooms and cocaine.
- The Last American Virgin (1982). Marijuana and Cocaine.
- The Last Days of Disco (1998).
- The Last Minute (2001). Heroin.
- Layer Cake (2004). Cocaine, crack cocaine and MDMA.
- Leaves of Grass (film) (2009). Marijuana.
- Leaving Las Vegas (1995). Cocaine.
- Lenny (1974). Heroin.
- Less Than Zero (1987). Cocaine.
- Lethal Weapon (1987). Cocaine and Heroin.
- Lethal Weapon 4 (1998). Nitrous Oxide (Laughing Gas).
- The Life Aquatic with Steve Zissou (2004). Marijuana.
- Life Is Hot in Cracktown (2009). Crack cocaine
- The Life of Rayful Edmond (2005). Cocaine, crack cocaine and marijuana.
- Light Sleeper (1992). Cocaine.
- Limitless (2011). Fictional drug called NZT48
- Liquid Sky (1982). Heroin.
- Little Fish (2005). Heroin.
- Little Miss Sunshine. Heroin, Viagra and anorectics referred to.
- Live and Let Die (1973). Heroin.
- Live Nude Girls (1995). Marijuana.
- Lock, Stock and Two Smoking Barrels (1998). Marijuana and cocaine.
- Loft (2008). Cocaine.
- London (2005). Cocaine and marijuana.
- London Boulevard (2010). Cannabis, Cocaine, Opium.
- Looking for Eric (2009) Marijuana
- Lord of War (2005). Cocaine and Brown-brown.
- Lords of Dogtown (2005). Marijuana.
- Lost in Translation (2003). Marijuana, possibly other psychedelics.
- Love Is The Drug (2006). Cocaine, prescription pills.
- Love Liza (2002). Gasoline fumes.
- Love. Blood. Kryptonite. (2008). Marijuana, cocaine.
Read more about this topic: List Of Drug Films