S
- Scrabble Blast! (2005) Game Boy Advance
- Sea Monsters: A Prehistoric Adventure (2007) Nintendo DS, Wii, PlayStation 2
- Shining Stars: Super Starcade (2008) Nintendo DS
- Showtime Championship Boxing (2007) Nintendo DS, Wii
- SimCity 2000 (2003) Game Boy Advance
- Smashing Drive (2004) Game Boy Advance
- Smuggler's Run (2002) Game Boy Advance
- Snood (2001) Game Boy Advance
- Snood 2: On Vacation (2005) Game Boy Advance, Nintendo DS
- Sorry! / Aggravation / Scrabble Junior (2005) Game Boy Advance
- Spy Hunter / Super Sprint (2005) Game Boy Advance
- Street Jam Basketball (2004) Game Boy Advance
Read more about this topic: List Of Destination Software Games