A
- AAXICO Airlines (1946 - 1965, to Saturn Airways)
- Access Air (1998 - 2001)
- ADI Domestic Airlines
- Aeroamerica (1974 - 1982)
- Aero Coach (1983 - 1991)
- Aero International Airlines
- Aeromech Airlines (1951 - 1983, to Wright Airlines)
- AeroSun International
- AFS Airlines (Arcata Flying Service)
- Air America (owned and operated by the CIA in Southeast Asia)
- Air America (1980s)
- Air Astro
- Air Atlanta (1981 - 88)
- AirAtlantic Airlines
- Air Bama
- Air Berlin, Inc. (Air Berlin USA) (1978-1990 )
- Airborne Express (1946 - 2003, to DHL)
- Air California, later AirCal (1967 - 87, to American Airlines)
- Air Carolina
- Air Central (Michigan)
- Air Central (Oklahoma) (to Trans-Central Airlines)
- Air Chaparral (1980 - 82)
- Air Chico
- Air Colorado
- Air Cortez (1977 - 86)
- Air Florida (1972 - 84)
- Air Gemini
- Air General
- Air Great Lakes
- Air Hawaii (1960s) (1960s)
- Air Hawaii (ceased operations in 1986)
- Air Hyannis
- Air Idaho
- Air Illinois (1970 - 1984)
- Air Iowa
- Airlift International (1946 - 81)
- Air Kentucky (1974 - 1989)
- Air L.A. Inc. (ceased operations 1995)
- Air-Lift Commuter
- Air Lincoln
- Air Link Airlines
- Air Link Airways
- Air Metro
- Air Miami (to North American Airlines)
- Air Michigan
- Air Mid-America
- Air Midwest (1965 - 2008)
- Air Missouri
- Air Molokai (1980s)
- Air Molokai (1990s)
- Air Molokai-Tropic Airlines
- Air Nebraska
- Air Nevada (1974 - 1998, to Pacific Wings)
- Air New England (1975 - 81)
- Air New Orleans (1981 - 88)
- Air Niagara (ceased operations 1984)
- Air North (Alaska)
- Air North (1963 - 1983, to Brockway Air)
- Air O'Hare
- Air Olympia
- Air Oregon (1979 - 1981, to Horizon Air)
- Air One (1990s)
- AirPac
- Air Pacific (USA) (1979 - 1981, to Golden Gate Airlines)
- Air Pennsylvania (1976 - 1982)
- Air Resorts Airline
- Air Sierra
- Air Solutions
- Air South (1969 - 1978, to Florida Airlines)
- Air South (1981-1982)
- Air South (1986-1987)
- Air South (1994-1997)
- Air Speed (1974)
- Air Spirit
- Air Sunshine (1970s)
- Air Sunshine (1980s)
- Air Texana
- Air Texas
- Air Trails
- Air 21
- Air US
- Air Utah
- AirVantage Airlines
- Air Vegas (1971 - 2004)
- Air Vermont (1981 - 1984)
- Air Virginia
- Airways of New Mexico
- Air West
- Alaska Air Transport (1935 to 1939) to Alaska Coastal Airlines
- Alaska Coastal Airlines (1939 - 1968) to Alaska Airlines
- Alaska Coastal-Ellis Airlines
- Albany Air
- All American Aviation (became Allegheny Airlines)
- Allegheny Airlines (became USAir)
- Aloha Airlines (1946 - 2008, passenger operations ceased, now a cargo only airline)
- Altair Airlines ceased in 1981
- America West Airlines (1981 - 2005, merged with US Airways)
- American Central Airlines
- American Export Airlines (1937 - 1945, merged the transatlantic division of American Airlines to form American Overseas Airlines)
- American Flyers Airline (1949 - 1971, to Universal Airlines)
- American International Airways (1984 - 1997, to Kitty Hawk International)
- American Overseas Airlines (1945 - 1950, merged into Pan American World Airways)
- Arista International Airlines
- Arizona Airways (1942 - 1950, to Frontier Airlines)
- Arizona Airways (1993-1996) (1993 - 1996, to Arizona Airways Express)
- Aroostook Airways (1970s)
- Arrow Air (1947 - 2010)
- Aspen Airways (1952 - 1990)
- Aspen Mountain Air (1996 - 1998) see Lone Star Airlines
- ATA Airlines (1973 - 2008)
- Atlantic Coast Airlines (1989 - 2006, to Independence Air)
- Atlantic Gulf Airlines (1983 - 1986)
- Austin Express (1997 - 2000)
Read more about this topic: List Of Defunct Airlines Of The United States