D
- Keon Daniel, Philadelphia Union
- Mamadou Danso, Portland Timbers
- Jun Marques Davidson, Vancouver Whitecaps FC
- Brad Davis, Houston Dynamo
- Simon Dawkins, San Jose Earthquakes †
- Julian De Guzman, FC Dallas
- A. J. DeLaGarza, Los Angeles Galaxy
- Nick DeLeon, D.C. United
- Marco Delgado, Chivas USA
- Jay DeMerit, Vancouver Whitecaps FC
- Tyler Deric, Houston Dynamo
- Dwayne De Rosario, D.C. United
- Cesar Diaz Pizarro, San Jose Earthquakes
- Digão, New York Red Bulls
- Bright Dike, Portland Timbers
- Alex Dixon, Houston Dynamo
- Landon Donovan, Los Angeles Galaxy
- Andy Dorman, New England Revolution
- Emiliano Dudar, D.C. United
- Dilly Duka, Columbus Crew
- Terry Dunfield, Toronto FC
- Todd Dunivant, Los Angeles Galaxy
- Andrew Duran, Seattle Sounders FC
- Dom Dwyer, Sporting Kansas City
- Andrew Dykstra, D.C. United
Read more about this topic: List Of Current Major League Soccer Players