Notable Clinical Studies
- British Doctors Study – in 1956 provided convincing statistical proof that tobacco smoking increased the risk of lung cancer.
- Framingham Heart Study – a cardiovascular study based in Framingham, Massachusetts, which began in 1948 with 5,209, and is now on its third generation of participants.
- Heart Protection Study – the largest study to investigate the use of statins in the prevention of cardiovascular disease.
- International Studies of Infarct Survival – four randomized controlled trials of several drugs for treating suspected acute myocardial infarction.
- Intersalt study – a landmark observational study that showed a strong association between dietary salt and risk of cardiovascular disease.
- JUPITER trial – the first clinical trial to demonstrate that statin therapy may provide benefit to patients with low-to-normal LDL levels and no known cardiovascular disease.
- Multicenter AIDS Cohort Study – a study of over 6,000 men infected with HIV that has been ongoing for over 25 years
- Stateville Penitentiary Malaria Study – a controlled study of the effects of malaria on the inmates of Stateville Penitentiary near Joliet, Illinois.
- Tuskegee Study of Untreated Syphilis in the Negro Male – a clinical study, conducted between 1932 and 1972 in Tuskegee, Alabama studied the natural progression of the disease if left untreated.
Read more about this topic: List Of Clinical Research Topics
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