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- Edmund Charles Tarbell – painter
- Lofa Tatupu – NFL linebacker
- James Taylor – Folk singer
- John Thomas – First man to clear 7 feet (2.1 m) in high jump
- Henry David Thoreau – Poet, novelist
- 'Til Tuesday – Band
- Jimmy Tingle – Stand-up comedian, actor
- Eve Torres - WWE Diva
- That Handsome Devil – Band
- Charles Tufts- founder of Tufts University
- John Tortorella – NHL Coach, Head Coach of the New York Rangers
- Touré – Writer, TV Host
- Uma Thurman – Actress
- Ralph Tresvant – Singer
- Kevin Trudeau – Author, pocket billiards promoter, salesman
- Jen Trynin – Musician
- Jonathan Tucker – Actor
- Maura Tierney – Actress
- John Tudor- MLB Pitcher, St. Louis Cardinals
Read more about this topic: List Of Bostonians