L
- 7L & Esoteric – Rap Group
- PJ Ladd – Professional skateboarder (Plan B Skateboards, éS Footwear)
- Jack Landron – Folksinger/Songwriter
- Lewis Howard Latimer – African American Inventor
- Denis Leary – actor, comedian, writer and director
- Emril Lagasse – Chef/TV Personality
- Dennis Lehane – author
- Jack Lemmon – Actor
- Letters To Cleo – rock band
- Elma Lewis – Founder of the National Center of Afro-American Artists (including a museum) and the Elma Lewis School of Fine Arts
- William Linn (soldier) - defender of the Alamo
- Lyte Funky Ones – Pop Trio
- Henry Cabot Lodge – Politician
- Edward Lawrence Logan – Military officer, jurist, and politician
- Howie Long – NFL player
- Robert Lowell – poet
- Amy Lawrence Lowell – (1874–1925) Pulitzer Prize winning Poet
- Phil Labonte – Musician ( all that remains)
- Jay Leno – Comedian
- Matt LeBlanc – Actor
- Adam Lundquist - Radio DJ
Read more about this topic: List Of Bostonians