Biotechnology Companies
- The following is a list of the top 100 companies ranked by revenue (2006). The first nine companies qualify for the list of the top 50 pharmaceutical companies.
Examining the list of the top 100 such companies, below, shows that many have negative income. This is consistent with the notion that only one in ten biotechnology companies were considered profitable in mid-2005.
| Rank 2006 | Company | Country | Revenue in 2006 | R&D in 2006 | Net income/ (loss) in 2006 | Employees in 2006 |
|---|---|---|---|---|---|---|
| 1 | Amgen | USA | 14,268.0 | 3,366.0 | 2,950.0 | 20,100 |
| 2 | Genentech | USA | 11,724.0 | 2,995.0 | 2,740.0 | 10,001+ |
| 3 | Genzyme | USA | 3,187.0 | 650.0 | (16.8) | 9,000+ |
| 4 | UCB | Belgium | 3,169.6 | 772.6 | 461.1 | 8,477 |
| 5 | Gilead Sciences | USA | 3,026.1 | 383.9 | (1,190.0) | 7,575 |
| 6 | Serono | Switzerland | 2,804.9 | 560.5 | 735.4 | 4,775 |
| 7 | Biogen Idec | USA | 2,683.0 | 718.4 | 217.5 | 3,750 |
| 8 | CSL | Australia | 2,148.3 | 119.1 | 86.8 | 2,895 |
| 9 | Cephalon | USA | 1,764.1 | 403.4 | 144.8 | 2,515 |
| 10 | MedImmune | USA | 1,276.8 | 448.9 | 48.7 | 2,359 |
| 11 | Celgene | USA | 898.9 | 258.6 | 69.0 | 1,864 |
| 12 | Abraxis BioScience | USA | 765.5 | 96.9 | (46.9) | 1,734 |
| 13 | Actelion | Switzerland | 754.6 | 169.0 | 192.4 | 1,550 |
| 14 | ImClone Systems | USA | 677.8 | 112.1 | 370.7 | 1,287 |
| 15 | Amylin Pharmaceuticals | USA | 510.9 | 222.1 | (218.9) | 1,100 |
| 16 | Millennium Pharmaceuticals | USA | 486.8 | 318.2 | (44.0) | 1,073 |
| 17 | PDL BioPharma | USA | 414.8 | 260.7 | (130.0) | 993 |
| 18 | OSI Pharmaceuticals | USA | 375.7 | 176.7 | (582.2) | 962 |
| 19 | MGI Pharma | USA | 342.8 | 100.1 | (40.2) | 947 |
| 20 | Pharmion | USA | 238.6 | 70.1 | (91.0) | 793 |
| 21 | Nektar Therapeutics | USA | 217.7 | 149.4 | (154.8) | 770 |
| 22 | Vertex Pharmaceuticals | USA | 216.4 | 371.7 | (206.9) | 760 |
| 23 | Biocon | India | 200.3 | 30.5 | 43.5 | 1,838 |
| 24 | Cubist Pharmaceuticals | USA | 194.7 | 57.4 | (0.4) | 746 |
| 25 | Enzon Pharmaceuticals | USA | 185.7 | 43.5 | 21.3 | 722 |
| 26 | QLT | Canada | 175.1 | 56.4 | (101.6) | 653 |
| 27 | ViroPharma | USA | 167.2 | 19.2 | 66.7 | 651 |
| 28 | Alkermes | USA | 166.6 | 89.1 | 3.8 | 617 |
| 29 | Crucell | Netherlands | 165.3 | 84.9 | (110.0) | 611 |
| 30 | United Therapeutics | USA | 159.6 | 57.6 | 74.0 | 585 |
| 31 | LifeCell | USA | 141.7 | 16.5 | 20.5 | 573 |
| 32 | Ligand Pharmaceuticals | USA | 141.0 | 41.9 | (31.7) | 540 |
| 33 | Myriad Genetics | USA | 114.3 | 83.8 | (38.2) | 511 |
| 34 | Exelixis | USA | 98.7 | 185.5 | (101.5) | 500 |
| 35 | Cangene | Canada | 96.8 | 22.1 | 11.6 | 498 |
| 36 | InterMune | USA | 90.8 | 103.8 | (107.2) | 492 |
| 37 | Nabi Biopharmaceuticals | USA | 89.9 | 37.6 | (58.7) | 487 |
| 38 | BioMarin Pharmaceutical | USA | 84.2 | 66.7 | (28.5) | 417 |
| 39 | Lexicon Pharmaceuticals | USA | 72.8 | 106.7 | (54.3) | 410 |
| 40 | Progenics Pharmaceuticals | USA | 69.9 | 61.7 | (21.6) | 410 |
| 41 | Innogenetics | Belgium | 67.5 | 32.1 | (31.5) | 371 |
| 42 | Idenix Pharmaceuticals | USA | 67.4 | 96.1 | (75.1) | 359 |
| 43 | MorphoSys | Germany | 66.6 | 21.9 | 7.6 | 336 |
| 44 | Omrix Biopharmaceuticals | USA | 63.8 | 3.4 | 23.1 | 335 |
| 45 | Regeneron Pharmaceuticals | USA | 63.4 | 137.1 | (102.3) | 323 |
| 46 | Acambis | UK | 57.0 | 68.2 | (30.4) | 285 |
| 47 | Tanox | USA | 56.1 | 53.4 | (2.6) | 285 |
| 48 | ViaCell | USA | 54.4 | 14.0 | (21.0) | 282 |
| 49 | Indevus Pharmaceuticals | USA | 50.5 | 43.2 | -50.6 | 279 |
| 50 | Medarex | USA | 48.6 | 194.5 | (181.7) | 277 |
| 51 | NPS Pharmaceuticals | USA | 48.5 | 68.4 | (112.7) | 276 |
| 52 | Monogram Biosciences | USA | 48.0 | 19.0 | (38.7) | 274 |
| 53 | Oscient Pharmaceuticals | USA | 46.2 | 12.4 | (78.5) | 267 |
| 54 | Array BioPharma | USA | 45.0 | 33.4 | (39.6) | 263 |
| 55 | AEterna Zentaris | Canada | 41.4 | 28.7 | 33.4 | 260 |
| 56 | IsoTis | Switzerland | 40.7 | 7.7 | (18.5) | 255 |
| 57 | Enzo Biochem | USA | 39.8 | 7.9 | (15.7) | 255 |
| 58 | CuraGen | USA | 39.6 | 58.5 | (59.8) | 254 |
| 59 | Neurocrine Biosciences | USA | 39.2 | 97.7 | (107.2) | 254 |
| 60 | MediGene | Germany | 38.4 | 26.7 | (8.7) | 248 |
| 61 | Life Therapeutics | Australia | 37.6 | 0.1 | (31.2) | 245 |
| 62 | Inspire Pharmaceuticals | USA | 37.1 | 42.5 | (42.1) | 238 |
| 63 | CV Therapeutics | USA | 36.8 | 135.3 | (274.3) | 233 |
| 64 | Cerus | USA | 35.6 | 29.5 | (4.8) | 208 |
| 65 | SciClone Pharmaceuticals | USA | 32.7 | 14.1 | 0.7 | 197 |
| 66 | ImmunoGen | USA | 32.1 | 40.9 | (17.8) | 197 |
| 67 | Protherics | UK | 30.9 | 11.8 | (16.5) | 196 |
| 68 | Arena Pharmaceuticals | USA | 30.6 | 103.4 | (88.3) | 195 |
| 69 | Vernalis | UK | 30.1 | 71.7 | (78.2) | 192 |
| 70 | Bavarian Nordic | Denmark | 29.5 | 19.9 | (27.1) | 191 |
| 71 | Xoma | USA | 29.5 | 52.1 | (51.8) | 189 |
| 72 | GPC Biotech | Germany | 28.5 | 81.3 | (80.4) | 180 |
| 73 | Micromet | USA | 27.6 | 28.3 | 0.0 | 171 |
| 74 | Targacept | USA | 27.5 | 21.8 | (1.2) | 170 |
| 75 | Carrington Laboratories | USA | 27.4 | 5.8 | (7.6) | 166 |
| 76 | Acorda Therapeutics | USA | 27.4 | 12.1 | (60.0) | 158 |
| 77 | Anika Therapeutics | USA | 26.8 | 3.6 | 4.6 | 156 |
| 78 | Human Genome Sciences | USA | 25.8 | 209.2 | (251.2) | 151 |
| 79 | Dusa Pharmaceuticals | USA | 25.6 | 6.2 | (31.3) | 150 |
| 80 | ZymoGenetics | USA | 25.4 | 128.5 | (130.0) | 150 |
| 81 | Maxygen | USA | 25.0 | 49.1 | (16.5) | 147 |
| 82 | Isis Pharmaceuticals | USA | 24.5 | 80.6 | (45.9) | 133 |
| 83 | Genmab | Denmark | 23.9 | 90.6 | (77.4) | 128 |
| 84 | BioSciMed | USA | 23.9 | 11.6 | (1.0) | 126 |
| 85 | Bioniche Life Sciences | Canada | 24.1 | 11.9 | (1.0) | 127 |
| 86 | Vitrolife | Sweden | 23.2 | 3.3 | 2.1 | 124 |
| 87 | Coley Pha | |||||
| 91 | Medivir Group | Sweden | 18.8 | 39.7 | (29.7) | 88 |
| 92 | Peptech | Australia | 18.7 | 4.6 | 3.8 | 85 |
| 93 | Ambrilia Biopharma | Canada | 17.4 | 8.3 | (2.1) | 85 |
| 94 | Cytogen | USA | 17.3 | 7.3 | (15.1) | 85 |
| 95 | Replidyne | USA | 16.0 | 38.3 | (34.6) | 79 |
| 96 | Sinovac Biotech | China | 15.4 | 0.3 | (0.7) | 67 |
| 97 | Trimeris | USA | 15.2 | 18.3 | 7.4 | 64 |
| 98 | Avanir Pharmaceuticals | USA | 15.2 | 29.2 | (62.6) | 64 |
| 99 | Adolor | USA | 15.1 | 56.7 | (69.7) | 51 |
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