S
- Argenis Salazar
- Luis Salazar
- Oscar Salazar
- Bill Samson
- Luis Sánchez
- Orlando Sánchez
- Jack Sanford
- Rafael Santana
- Benito Santiago
- José Santiago
- José (Palillo) Santiago
- José (Pantalones) Santiago
- Manny Sarmiento
- Steve Sax
- Pat Scantlebury
- Hank Schenz
- Mike Schmidt
- Mike Scioscia
- Marco Scutaro
- Jeff Sellers
- Wilmer Shantz
- Bob Shaw
- Don Shaw
- Razor Shines
- Candy Sierra
- Rubén Sierra
- Randall Simon
- Wayne Simpson
- Bob Skinner
- Dave Smith
- Hal Smith
- Jerry Snyder
- Julio Solano
- Alay Soler
- Sammy Sosa
- Mario Soto
- Cliff Speck
- Daryl Spencer
- Ed Spiezio
- Mike Stanton
- Dick Starr
- Jeff Stone
- Dave Stewart
- Mike Sweeney
Read more about this topic: List Of Baseball Players Who Have Played In The Caribbean Series