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- "M&M Boys" =
- Originally, teammates Roger Maris and Mickey Mantle, American right fielder and center fielder respectively
- Later, teammates Joe Mauer and Justin Morneau, American catcher and Canadian first baseman respectively
- "Mad Bum" = Madison Bumgarner, American starting pitcher
- "Mad Dog" = Greg Maddux, American starting pitcher
- "The Mad Hungarian" = Al Hrabosky, American closer
- "The Mahatma" = Branch Rickey, American baseball executive
- "Marvelous Marv" = Marv Throneberry, United States baseball player
- "The Mayor" = Sean Casey, United States baseball player
- "Melk Man" = Melky Cabrera, United States baseball player
- "The Mick" = Mickey Mantle, American outfielder
- "Mickey" =
- Gordon Cochrane, American catcher and manager
- John Rivers, United States baseball player
- "Miggie" = Miguel Cabrera, Venezuelan baseball player
- "Minnie" = Saturnino MiƱoso Arrieta, Cuban baseball player
- "Mr. Cub" = Ernie Banks, American shortstop and first baseman. So nicknamed because he played his entire Major League career with the Chicago Cubs.
- "Mr. March" = Alex Rodriguez, American shortstop and third baseman
- "Mr. May" = Dave Winfield, American outfielder (derogatory). Given the nickname by several sportswroters because they believed he peaked too early in the season.
- "Mr. October" = Reggie Jackson, American outfielder. Given the nickname after hitting four home runs in a single World Series game, a record that still stands to this day.
- "Mr. November" = Derek Jeter, American shortstop. The first MLB player to hit a World Series home run in the month of November.
- "Mo" = Mariano Rivera, Panamanian closer
- "Mookie" = William H. Wilson, United States baseball player
- "Moose" =
- Mike Mussina, American starting pitcher
- Bill Skowron, American first baseman
- "Mudcat" = Jim Grant, American starting pitcher
- "Muggsy" = Gary Allenson, United States baseball player
- "Mysterious" = Frederick Walker, United States baseball pitcher & baseball, basketball, & football coach
- "Mr. Sweet Swing" = Joe Mauer, American catcher
Read more about this topic: List Of Baseball Player Nicknames