S
- The Scaffold. 60s group featuring Mike McGear, Roger McGough and John Gorman. Had a Number 1 with "Lily the Pink", and other hits with "Thank You Very Much", "Do You Remember?", and "Gin Gan Goolie" in the 1960s and "Liverpool Lou" in the 70s.
- The Seal Cub Clubbing Club: Current post-punk band often compared to the likes of The Fall and Radiohead.
- The Searchers: 60s Merseybeat group. No. 1 Hits include "Sweets For My Sweet", "Needles And Pins" and "Don't Throw Your Love Away".
- Shack: Cult band led by Mick Head, formerly of The Pale Fountains. Highly influential on Britpop bands such as Oasis. Noel Gallagher repaid the debt by signing them to his record label.
- Short Sharp Shock: Crossover hardcore/thrash band from Wirral/Liverpool.
- Skinny - 1995 to 1998 90's Indie pop band later known as Monochrome
- Smaller - Mid 90's Indie band featuring Digsy of Oasis fame
- Sonia: Pop singer from the PWL stable. Born in Skem but mostly associated with Liverpool.
- Space: 1990s indie-rock band best known for "Female of the Species" and their 6 other Top 20 hit singles.
- The Stands: 2000s rock'n'roll band led by songwriter Howie Payne. Split in 2006.
- Rory Storm and the Hurricanes: Merseybeat group.
- Supercharge: 1970s funk/rock band, led by Albie Donnelly and featuring Ozzie Yue
- The Swinging Blue Jeans: 60s Merseybeat group. Top 3 Hits include "Hippy Hippy Shake" and "You're No Good".
- Second Chance : pop punk from Rainhill.
Read more about this topic: List Of Bands From Merseyside