S
- Catherine Sakai
- Luis Santiago
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- President of the Earth alliance at the beginning of the series. His openness to peaceful relationships with alien races contrasts with that of Vice President Clark, who hid his xenophobic views until he became president after Santiago's assassination in 2259.
- Senna
- Anna Sheridan
- David Sheridan
- John Sheridan
- Jeffrey Sinclair
Read more about this topic: List Of Babylon 5 Characters