Si
- Charles E. Silberman (1925–2011)
- Ron Silliman (born 1946)
- Burton Silver
- Robert Silverberg (born 1935)
- Roger Silverwood (Creator of DI Angel)
- Shel Silverstein (1930–1999)
- Clifford D. Simak (1904–1988)
- Simeon Simev (born 1949)
- Dan Simmons (born 1948)
- Francesca Simon (born 1955)
- Les Simons (pseudonym of Kathryn Ptacek)
- Clive Sinclair (born 1948)
- Rebecca Sinclair
- Isaac Bashevis Singer (1902–1991)
- Marilyn Singer (born 1948)
- Jaspreet Singh (born 1969)
- Johanna Sinisalo (born 1958)
- James Sites (born 1924)
- Susan Sizemore
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