S
- Saliva (1)
- Josey Scott (1)
- Seether (2)
- Semisonic (1)
- Shinedown (1)
- Silverchair (1)
- Silversun Pickups (1)
- Simple Minds (1)
- Siouxsie and the Banshees (2)
- The Sisters of Mercy (1)
- Smash Mouth (1)
- The Smashing Pumpkins (1)
- Soul Asylum (2)
- Staind (3)
- Sting (1)
- Stone Temple Pilots (1)
- Sublime (1)
- Sugar Ray (2)
- The Sugarcubes (1)
- Sum 41 (1)
- The Sundays (1)
- System of a Down (2)
Read more about this topic: List Of Artists Who Reached Number One On The U.S. Alternative Rock Chart